Beilstein J. Nanotechnol.2019,10, 1826–1832, doi:10.3762/bjnano.10.177
longa that has been used in antitumor and anti-inflammation applications, exhibits very limited water solubility and rapid in vivo degradation, which limits its clinical application. To overcome these limitations, niosome nanoparticles were prepared by microfluidicmixing for curcumin encapsulation
electron microscopy. Curcumin was encapsulated with a maximum encapsulation efficiency of around 60% using Tween 85 as the non-ionic surfactant. Niosomes prepared by microfluidicmixing provided a controlled release of curcumin, as indicated by the release profile of curcumin, improving its therapeutic
capability. These results demonstrate that niosomes prepared by microfluidicmixing to encapsulate curcumin are a promising delivery system to reach target cells.
Keywords: curcumin; drug delivery; microfluidicmixing; niosomes nanoparticle; Introduction
Curcumin is a natural product that is derived from
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Figure 1:
TEM images of (A) SP80 niosomes prepared at 1:1 FRR, (B) SP80 niosomes prepared at 3:1 FRR, (C) T85...